Medicinal Chemistry is a discipline that involved with search,discovery, design, identification, and synthesis of biologically active compounds (drugs), drug metabolism study, interpretation of drug mechanism of action at molecular level, and chemical structure-activity relationships (SAR) of serial compounds. Medicinal chemistry is a highly interdisciplinary science combining chemistry, biology, medical, and pharmaceutical sciences.
Research activities in medicinal chemistry is important for the development of Indonesia, especially in health area, i.e. in finding new drugs, either from natural resources or synthetic compounds. Discovery of drugs are generally started from screening of natural materials traditionally used for treatment of illness, followed by isolation of active compounds, followed by semi-synthesis or total synthesis of the compounds. The active compound can be used as lead compound to be further developed to the more active and more selective compounds, with minimum side effect and toxicity, through rational drug design. Before synthesis, in silico study of interaction between drug and receptor using modern computer program (molecular modeling) is important to minimize trial and error. Then study on relationship between structure, chemical properties (lipophilic, electronic, and steric) and biological activity is carried out either two or three dimensionally.
Considering the importance of those issues, University of Indonesia Faculty of Pharmacy, Airlangga University Faculty of Pharmacy, Gadjah Mada University Faculty of Pharmacy, ITB School of Pharmacy, Indonesian Medicinal Chemists Association (PERAKMI), and Indonesian Institute of Science (LIPI) will jointly hold International Conference on Medicinal Chemistry and Timmerman Award 2013.
The theme of the conference is “Exploring Lead Compounds from Nature Biodiversity in Drug Discovery“. Hopefully this conference will give positive impacts in enhancing the role of medicinal chemistry in drug development in Indonesia.
At the end of the conference, Timmerman Award will be presented to the outstanding Indonesian young chemists working in medicinal chemistry. There will be a prize for the best poster presentation
This conference is organized by Faculty of Pharmacy, University of Indonesia and PERAKMI